OBJECTIVE: To determine whether healthy humans can adequately compensate for sugar-sweetened beverage (SSB) calorie intake through reductions in solid food intake, and whether fructose content affects the degree of compensation.
OBJECTIVE: To investigate the separate effects of habitual exercise differing in amount and intensity on abdominal obesity and glucose tolerance to determine whether there is added benefit from performing the same amount of exercise at a higher intensity. More “Effects of exercise amount and intensity on abdominal obesity and glucose tolerance in obese adults: a randomized trial”
OBJECTIVE: To evaluate the metabolic effects of substituting a dairy beverage (milk) and a dairy food (yogurt) for a sugar-sweetened beverage (soda) and a sugar-sweetened non-dairy-food (non-dairy pudding), in order to test the hypothesis that consumption of dairy products compared with sugar sweetened products (SSPs) would favourably affect insulin sensitivity and pancreatic beta-cell function in habitual consumers of high-sugar beverages. More “Sugar-sweetened product consumption alters glucose homeostasis compared with dairy product consumption in men and women at risk of type 2 diabetes mellitus”
OBJECTIVE: To study the effects of non-caloric artificial sweeteners (NAS) on the composition and function of the colonic microbiota, and the resultant effects on host glucose metabolism.
More “Artificial sweeteners induce glucose intolerance by altering the gut microbiota”
OBJECTIVE: To compare the metabolic health effects (insulin sensitivity, insulin secretion, insulin clearance, triacylglycerol and cholesterol concentrations) of short-term (2-week) consumption of high fructose (HF) and high glucose (HG)-sweetened beverages in adolescents aged 15-20 years.
OBJECTIVE: To investigate the short-term effects of glucose and sucrose on cognitive performance and mood in healthy elderly people with self-reported memory complaints. Whether there was a differential effect of glucose or sucrose on cognitive performance between participants with better vs a poorer glucose recovery.
More “Short-term effects of glucose and sucrose on cognitive performance and mood in elderly people”
Objective: To update a series of systematic reviews and meta-analyses of controlled feeding trials to assess the cardiometabolic effects of fructose in isocaloric exchange for glucose.
More “Fructose vs. glucose and metabolism: do the metabolic differences matter?”
Objective: To study neurophysiological factors that might underlie associations between fructose consumption and weight gain.
More “Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways”
Objective: To examine the effects of short-term over-feeding diets high in glucose, fructose or saturated fat on intra-hepatocellular lipid (IHCL) and markers of hepatic insulin sensitivity.
More “Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans”
Objective: To compare the effects on liver fat levels of glucose and fructose under either isocaloric or hypercaloric conditions